BIS – ProShares UltraShort Nasdaq Biotechnology
ProShares UltraShort Nasdaq Biotechnology (BIS) is a Trading--Inverse Equity ETF, issued by ProShares, $2.5M in assets, 0.95% expense ratio.
Returns as of Oct 23, 2026: 1 week -5.2%, 1 year -47.4%.
Aims for daily returns inverse to Nasdaq Biotechnology Index. Invests in financial instruments for this goal.
Top holdings
- AMGN – Amgen Inc, 8.1%
- GILD – Gilead Sciences Inc, 7.4%
- VRTX – Vertex Pharmaceuticals Inc, 7.2%
- BIIB – Biogen Inc, 6.1%
- ILMN – Illumina Inc, 5.7%
- REGN – Regeneron Pharmaceuticals Inc, 4.1%
- ALXN – Alexion Pharmaceuticals Inc, 3.0%
- SGEN – Seagen Inc, 2.2%
- INCY – Incyte Corporation, 2.1%
- BMRN – Biomarin Pharmaceutical Inc, 1.9%
- ALNY – Alnylam Pharmaceuticals Inc, 1.6%
- MYL – Viatris Inc, 1.4%
- SNY – Sanofi ADR, 1.3%
- NBIX – Neurocrine Biosciences Inc, 1.2%
- SRPT – Sarepta Therapeutics Inc, 1.1%
- NVCR – Novocure Ltd, 1.1%
- JAZZ – Jazz Pharmaceuticals PLC, 1.0%
- IONS – Ionis Pharmaceuticals Inc, 1.0%
- TECH – Bio-Techne Corp, 1.0%
- GH – Guardant Health Inc, 1.0%
- HZNP – Horizon Pharma PLC, 0.9%
- AMRN – Amarin Corporation PLC, 0.8%
- MRNA – Moderna Inc, 0.8%
- BGNE – BeiGene Ltd, 0.8%
- PRAH – PRA Health Sciences Inc, 0.8%